The Immunobiology Lab at MGH is currently conducting multiple clinical trials using Bacillus Calmette-Guérin (BCG), an inexpensive generic drug, as a treatment for advanced type 1 diabetes. The BCG clinical trial program has been underway for almost 10 years. To date, more than 230 patients with longstanding type 1 diabetes have been enrolled in BCG clinical trials. A 150-patient, randomized, placebo-controlled, Phase II clinical trial is currently fully enrolled and all patients have been followed for at least one year.
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